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Nicole Parlett
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What My First Week in a Research Lab Actually Looked Like

Before starting in the lab, I assumed the first week would be mostly hands-on — learning techniques, running gels, getting comfortable at the bench. In practice, most of it was reading: papers, protocols, and old lab notebooks, trying to understand not just how an experiment was done but why it was designed that way.

A few things stood out:

  • Protocols are living documents. The version taped above the bench was rarely the final word — most experienced lab members had their own small modifications, and part of the first week was learning which ones actually mattered.
  • Troubleshooting is the real skill. Anyone can follow a protocol once. The difference between a novice and an experienced researcher showed up when something didn’t work — knowing which step to suspect first.
  • Documentation matters more than I expected. A clearly written notebook entry from a year ago saved me hours of guessing when I needed to repeat someone else’s experiment.

I’ll probably write more of these as the semester goes on — partly for my own reference, partly because I wish I’d had more first-person accounts like this before I started.